Language Function in Patients With Brain Tumors

Memorial Sloan Kettering Cancer Center (MSK)

Status: Completed

Conditions: CNS Cancer; Brain Cancer

Treatments: Other: fMRI Scan, pre- and post language evaluation

Study type: Observational

Funder types: Other

Identifiers

NCT00599703

05-043

Details and patient eligibility

About

The purpose of this study is to use an imaging method called functional magnetic resonance imaging (fMRI) in patients who have a tumor near an area of the brain that is believed to control language. The fMRI is a new kind of imaging that uses a strong magnetic field to look at functioning brain tissue. This kind of imaging will be used to study the effect of the brain tumor on your speech.

Enrollment: 7 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient in whom a tumor invades or is directly adjacent to the expected location of one of the language centers.
• At least 18 years of age
• English as first language

Exclusion criteria

• Patients with high grade tumors
• History of significant psychiatric condition (e.g. schizophrenia, obsessive-compulsive disorder, significant dementia),
• History of the following neurological conditions: CVA, demyelinating conditions, cerebral palsy, Alzheimer's disease.
• History of significant claustrophobic reactions.
• Pregnancy
• Standard contraindications to MR examinations (e.g. implanted stimulator)
• Patients, who were treated prior to our first scan, will not be eligible to participate in this study

Trial design

7 participants in 1 patient group

1

Description:

neurosurgical patients

Treatment:

Other: fMRI Scan, pre- and post language evaluation