Laparoscopic Antireflux Surgery Versus Endoscopic Full-thickness Gastroplication for Gastroesophageal Reflux Disease (GERD)

General Public Hospital Zell am See

Status

Completed

Conditions

Gastroesophageal Reflux Disease

Treatments

Procedure: anti-reflux surgery

Study type

Interventional

Funder types

Other

Identifiers

NCT01324791

Zell02

Details and patient eligibility

About

Endoscopic full thickness gastroplication (Plicator-Procedure) has the potential to be a safe and effective alternative to laparoscopic antireflux surgery (LARS)to improve symptoms of GERD. This prospective randomized study compares objective and subjective outcome parameters of Plicator with that of LARS.

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

long history of GERD symptoms
persistent or recurrent symptoms despite optimal medical treatment
persistent or recurrent complications of GERD
reduced quality of life owing to increasing esophageal exposure to gastric juice
pathological values in the preoperative evaluated functional parameters.

Exclusion criteria

any distinct hiatal hernia detectable by gastroscopy or barium radiography
dysphagia
esophageal strictures
poor physical status (American Society of Anesthesiologists (ASA) scores III and IV) and pregnancy.