Laparoscopic-Assisted Transanal Pull-Through for Hirschsprung Disease in Pediatric:Short and Intermediate Outcomes of Two Different Techniques

Al-Azhar University

Status and phase: Completed; Phase 4

Conditions: Hirschsprung Disease

Treatments: Procedure: laparoscopic-assisted Swenson-like (LASwL); Procedure: laparoscopic-assisted Soave (LASo)

Study type: Interventional

Funder types: Other

Identifiers

NCT07186647

Ped. -Surg.-77MED.-Research-00

Details and patient eligibility

About

Compare the functional and surgical outcomes of laparoscopic-assisted Swenson-like (LASwL) and laparoscopic-assisted Soave (LASo) pull through in children with HD.

Full description

A prospective, randomized study was conducted involving 80 patients diagnosed with HD at Al-Azhar University Hospitals over a 48-month period from September 2020 to August 2024. Participants were randomly allocated to the LASwL (Group A) or LASo (Group B). The primary outcome was the postoperative bowel function score. Secondary outcomes included operative time, blood loss, duration of hospital stay, and incidence of postoperative Hirschsprung-associated enterocolitis (HAEC).

Enrollment: 40 patients

Sex: All

Ages: 1 month to 14 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• infants and children diagnosed with Hirschsprung's disease (HD) at the Department of Pediatric Surgery, Al-Azhar University Hospitals, from September 2020 to August 2024

Exclusion criteria

• Patients with ultrashort or total colonic aganglionosis and those who had previously undergone pull-through procedures

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

40 participants in 2 patient groups

Group A

Active Comparator group

Description:

20 patients with HD

Treatment:

Procedure: laparoscopic-assisted Swenson-like (LASwL)

Group B

Active Comparator group

Description:

20 patients with HD

Treatment:

Procedure: laparoscopic-assisted Soave (LASo)