Laparoscopic Clipping Versus Extracorporeal Ligation in Complicated Appendicitis Upper Egypt Overview

Assiut University

Status: Not yet enrolling

Conditions: Appendicitis

Treatments: Procedure: Laparoscopic appendectomy using extracorporeal ligation to secure the base of the appendix.; Procedure: Laparoscopic appendectomy using clipping.

Study type: Interventional

Funder types: Other

Identifiers

NCT05637554

Laparoscopic appendectomy.

Details and patient eligibility

About

The investigators aim to compare between laparoscopic clipping and extracorporeal ligation in complicated appendicitis regarding safety, efficacy, operative time, postoperative outcome, hospital stay and complications.

Full description

Appendectomy has become one of the most commonly performed emergency abdominal operations since it's description by McBurney in the 1890s. Since laparoscopic appendectomy was first described in 1983, there is an increase in the general trend towards performing this surgery using laparoscopy instead of open technique as this approach shows better pain score, lesser use of analgesics, less operative complications, better post operative recovery, less hospital stay and rapid return to normal work.

There are many methods for securing the base of the appendix, some of which are expensive others are not available or technically demanding. In this study the investigators aim to compare between extracorporeal ligation and clipping techniques regarding feasibility, safety, efficacy, operative time, postoperative outcome and complications especially in complicated appendicitis.

AS management of complicated appendicitis laparoscopically is possible, secure and can lead to a little occurrence of infectious complications, fewer post-operative pain, quick revival and improve cosmesis so the investigators will do a prospective clinical trial comparative study between two common techniques to determine the best one in management of complicated cases.

Enrollment: 40 estimated patients

Sex: All

Ages: 7 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Acute complicated appendicitis.
• Perforated appendicitis (diagnosed intraoperatively)
• Patients who will undergo laparoscopic appendectomy.

Exclusion criteria

• Patients with straight forward appendectomy.
• Patients who are not fit for laparoscopic appendectomy.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Laparoscopic clipping appendectomy

Active Comparator group

Description:

This group will undergo laparoscopic clipping of the base of the appendix during laparoscopic appendectomy.

Treatment:

Procedure: Laparoscopic appendectomy using clipping.

Laparoscopic extracorporeal ligation appendectomy

Active Comparator group

Description:

This group will undergo laparoscopic extracorporeal ligation of the base of the appendix during laparoscopic appendectomy.

Treatment:

Procedure: Laparoscopic appendectomy using extracorporeal ligation to secure the base of the appendix.