Laparoscopic Complete Mesocolic Excision on Colon Cancer (LCME)

Bo Feng

Status: Completed

Conditions: Quality of Life; Operation Finding; Complications; Pathology; Neoplasms Recurrence

Treatments: Procedure: D3-laparoscopic colectomy; Procedure: laparoscopic complete mesocolic excision

Study type: Interventional

Funder types: Other

Identifiers

NCT01628250

SH-MIS

Details and patient eligibility

About

Laparoscopic complete mesocolic excision is a concept that using laparoscopic surgery technique to perform a resection for colon cancer. Besides, the segment of the colon containing the tumor, the resection area should include an intact mesocolon as an envelope to encase the possible route for metastasis. The routes include blood vessels, lymphatic drain and etc. Such hypothesis predicts better histopathological and higher oncological results which turns into better survival rate and better quality of life.

Enrollment: 99 patients

Sex: All

Ages: 18 to 79 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with pathologically confirmed colon cancer
• Signed consent

Exclusion criteria

• History of malignancy
• Intestinal obstruction or perforation
• Evidence of metastasis by preoperative examinations
• Deformity of spine
• Emergency case
• BMI > 29

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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99 participants in 2 patient groups

laparoscopic complete mesocolic excision

Active Comparator group

Description:

Randomized group of patients receiving laparoscopic colectomy with the concept of complete mesocolic excision

Treatment:

Procedure: laparoscopic complete mesocolic excision

D3 laparoscopic colectomy

Active Comparator group

Description:

Randomized group of patients receiving laparoscopic colectomy with D3-resection

Treatment:

Procedure: D3-laparoscopic colectomy