Laparoscopic Guided Peri-wound Transversus Abdominis Plane Block With Bupivacaine Versus Local Wound Infiltration on Post-op Opioid Use in Laparoscopic Sleeve Gastrectomy

Khon Kaen University

Status and phase: Enrolling; Phase 3; Phase 2

Conditions: Laparoscopic Sleeve Gastrectomy; Bupivacine; Opioid Use; Morbid Obesity; Local Wound Infiltration; Transversus Abdominis Plane Block

Treatments: Procedure: Local wound infiltration; Procedure: peri-wound Transversus Abdominis Plane Block

Study type: Interventional

Funder types: Other

Identifiers

NCT05930184

HE651586

Details and patient eligibility

About

The goal of this randomized controlled trial is to compare laparoscopic guided peri-wound Transversus Abdominis Plane Block and bupivacaine versus local wound infiltration effect on reducing post-op opioid use in Laparoscopic Sleeve gastrectomy. The main questions it aims to answer are:

• Can laparoscopic guided peri-wound Transversus Abdominis Plane Block reduced post operative morphine usage when comparing with local wound port site infiltration.

Participants will be randomize into 2 group

• peri-wound Transversus Abdominis Plane Block
• local wound port site infiltration

Enrollment: 98 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient undergoing LSG at Sringarind hospital as indicated by Thai guideline

Exclusion criteria

• Allergic/contraindicated to bupivacaine, morphine, fentanyl, NSAIDs or Nefopam
• Unable to describe pain score Opioid addict
• denied consent

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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98 participants in 2 patient groups

local wound infiltration

Active Comparator group

Description:

0.25% Bupivacaine 20ml was injected into the wound subcutaneous tissue after the laparoscopic port was removed

Treatment:

Procedure: Local wound infiltration

peri-wound Transversus Abdominis Plane Block

Experimental group

Description:

0.25% Bupivacaine 20ml was injected into the transversus abdominis plane around the wound before the laparoscopic port was removed

Treatment:

Procedure: peri-wound Transversus Abdominis Plane Block