Laparoscopic Nissen Versus Toupet Fundoplication: Objective and Subjective Results of a Prospective Randomized Trial

General Public Hospital Zell am See

Status: Completed

Conditions: Laparoscopic Antireflux Surgery; Gastroesophageal Reflux Disease

Treatments: Procedure: laparoscopic anti-reflux surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT01321294

Zell01

Details and patient eligibility

About

The aim of this study is to compare subjective and objective outcome and surgical "side effects" of Nissen and Toupet fundoplication performed in a single institution by only two surgeons and to compare pre and postoperative findings to healthy individuals.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of gastroesophageal reflux disease
• Long history of GERD symptoms
• Persistent or recurrent symptoms despite optimal medical treatment
• Persistent or recurrent complications of GERD
• Reduced quality of life owing to increasing esophageal exposure to gastric juice
• Pathological values in the preoperative evaluated functional parameters

Exclusion criteria

• Previous esophageal or gastric surgery
• Poor physical status (American Society of Anesthesiologists (ASA) scores III and IV)
• Pregnancy

Trial design

0 participants in 2 patient groups

Nissen fundoplication

Active Comparator group

Treatment:

Procedure: laparoscopic anti-reflux surgery

Toupet fundoplication

Active Comparator group

Treatment:

Procedure: laparoscopic anti-reflux surgery