Laparoscopic Pancreatoduodenectomy Versus Open Pancreatoduodenectomy

Tongji Hospital

Status: Completed

Conditions: Resectable Lesions Located in the Pancreatic Head or Periampullary Region

Treatments: Procedure: pancreatoduodenectomy

Study type: Observational

Funder types: Other

Identifiers

NCT05520606

TJDBPS11

Details and patient eligibility

About

This is a single, retrospective, real-world study to investigate the surgical outcomes of minimally invasive pancreatoduodenectomy and open pancreatoduodenectomy, with the perioperative characteristics and long-term overall survival being compared. The investigators aimed to find out whether the minimally invasive surgery is safe and feasible for resectable lesions located in the pancreatic head and periampullary region. And the investigators also want to find out patients with what kind of characteristic can be benefit from the minimally invasive surgery compared with the open approach.

Full description

Pancreatoduodenectomy (Whipple surgery) is a complex surgical procedure and has been accepted as the gold standard treatment for resectable lesions of the pancreatic head and periampullary region.To date, how surgeons can safely pass the learning curve of laparoscopic pancreatoduodenectomy (LPD) without potentially harming patients remains a question. Around this topic, the investigators designed real-world study in a single center to retrospectively collect the PD surgeries since July 2014. The investigators aimed to find out whether the minimally invasive surgery is safe and feasible for resectable lesions located in the pancreatic head and periampullary region. And the investigators also want to find out patients with what kind of characteristic can be benefit from the minimally invasive surgery compared with the open approach. Besides, the investigators also want to investigate the clinical characteristics of patients and perioperative outcomes of LPD procedures and aimed to develop and validate a difficulty scoring system for patient selection which could help facilitate a comprehensive and security understanding of LPD for surgeon during different stage of the learning curve.

Enrollment: 800 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Aged 18 to 80 years.
2. Patients underwent PD surgeries.

Exclusion criteria

1. Peritoneal seeding or metastasis to distant sites;
2. Incomplete clinical data.

Trial design

800 participants in 2 patient groups

minimally invasive surgery

Description:

laparoscopic pancreatoduodenectomy.

Treatment:

Procedure: pancreatoduodenectomy

open surgery

Description:

open pancreatoduodenectomy

Treatment:

Procedure: pancreatoduodenectomy