Laparoscopic Tubal Patency Assessment

Pourmatroud, Elham, M.D.

Status: Completed

Conditions: Laparoscopy; Tubal Patency; Methylene Blue

Treatments: Drug: metheylne blue with normal saline; Drug: methylen blue &normal saline; Drug: methylene blue

Study type: Interventional

Identifiers

NCT01725477

Methylen blue in laparoscopy (Registry Identifier)

Methylen blue

Details and patient eligibility

About

1. Methylene blue in laparoscopy use for tubal patency assessment
2. Methylene blue could have negative effect on sperm motility, oocyte granulosa cell and fertility.
3. tubal washing after Methylene blue administration could be effective in pregnancy rate after operation.

Full description

women with unexplained infertility and without any problem during laparoscopy and hysteroscopy entered in the study.After randomization in one group after dye test,washing with normal saline was done until all of visible Methylene blue removed.In second group washing with normal saline did not done. pregnancy rate until three months after operation was followed without any intervention.

Enrollment: 30 patients

Sex: Female

Ages: 20 to 38 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• women with unexplained infertility

Exclusion criteria

• any intervention during operation like ovarian drilling or septum resection

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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30 participants in 2 patient groups

Dye& normal saline/ 20ml methylene blue +50 ml normal saline

Experimental group

Description:

first arm:20 ml methylene blue washing with50 ml normal saline

Treatment:

Drug: metheylne blue with normal saline

Drug: methylen blue &normal saline

Drug: methylene blue

injection of 20ml metheylen blue

Active Comparator group

Description:

20 ml methylene blue injected without washing

Treatment:

Drug: methylene blue