Laparoscopic Versus Open Left Hemihepatectomy for Liver Benign Lesions

Zhejiang University

Status: Completed

Conditions: Benign Lesions in Left Liver

Treatments: Procedure: Open left hemihepatectomy; Procedure: Laparoscopic left hemihepatectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT01768728

SRRSH20121225-1

Details and patient eligibility

About

The purpose of this study is to investigate the influence of the laparoscopic and open left hemihepatectomy on acute surgical trauma and stress response.

Enrollment: 60 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient with benign lesions who requires left hemihepatectomy
• Child-Pugh classification of A to B
• American Society Of Anesthesiologists (ASA) grading of I to III
• a body mass index of between 18 and 35
• willingness to participate in the study
• able to understand the nature of the study and what will be required of them

Exclusion criteria

• pregnant or lactating women
• unwillingness to participate
• Child-Pugh classification of C
• ASA grading of IV to V
• with condition of acute inflammatory,fever or diabetes mellitus
• with autoimmune disease or immunodeficiency
• taking drugs that affect the immune system

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

Laparoscopic left hemihepatectomy group

Active Comparator group

Description:

Group of patients that are operated with laparoscopic left hemihepatectomy

Treatment:

Procedure: Laparoscopic left hemihepatectomy

Open left hemihepatectomy

Active Comparator group

Description:

Group of patients operated with open left hemihepatectomy

Treatment:

Procedure: Open left hemihepatectomy