Laparoscopy in Children: Does it Decrease the Metabolic, Endocrine and Inflammatory Stress Response to Surgery

Institute of Child Health

Status: Completed

Conditions: Gastro-Oesophageal Reflux

Treatments: Procedure: open Nissen fundoplication; Procedure: Laparoscopic fundoplication

Study type: Interventional

Funder types: Other

Identifiers

NCT00231543

99SG92

Details and patient eligibility

About

The aim of this trial was to characterise the intra and post operative metabolic, endocrine and inflammatory response to laparoscopic fundoplication in children. We are testing the hypothesis that laparoscopic fundoplication is associated with a lack of hypermetabolism and catabolism and blunting of the endocrine/inflammatory stress response

Sex: All

Ages: 1 month to 16 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• infants and children with gastro-oesophageal reflux

Exclusion criteria

• septic shock, multi-organ dysfunction syndrome, cardiac, renal or congenital metabolic abnormalities

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind