LARS for Chinese Patients

Sun Yat-sen University

Status: Completed

Conditions: Incidence and Risk Factors of Low Anterior Resection Syndrome

Treatments: Diagnostic Test: LARS questionnaire

Study type: Observational

Funder types: Other

Identifiers

NCT05373602

LARS001

Details and patient eligibility

About

Low anterior resection syndrome (LARS) frequently occurs in patients undergoing low anterior resection (LAR). However, the incidence, exact mechanism and risk factors of major LARS largely variate in different studies. Considering varieties and differences of patient characteristics between Chinese patients and the western ones, this retrospective study aims to investigate the incidence of LARS in Chinese patients undergoing laparoscopic LAR, and to explore perioperative risk factors that might be associated with major LARS. Consequent patients undergoing laparoscopic LAR and free from disease recurrence from January 2015 to May 2021 were issued with LARS questionnaire. Incidence of LARS and patient data were collected and analyzed.

Enrollment: 261 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Patients diagnosed as rectal cancer and underwent radical laparoscopic LAR and straight colorectal/coloanal anastomosis (with or without a protective stoma) by a same surgical team

Exclusion criteria

either local or distal recurrence, severe complications such as postoperative anastomotic leakage, failure of protective stoma closure, data missed and no responding to LARS questionnaire