LARS in Ovarian Cancer Patients

Medical University of Vienna

Status: Completed

Conditions: Low Anterior Resection Syndrome

Treatments: Other: low anterior resection syndrome evaluation

Study type: Observational

Funder types: Other

Identifiers

NCT04279080

1201/2018

Details and patient eligibility

About

Background:

Low anterior resection syndrome (LARS) is a common functional disorder after low anterior resection impacting quality of life. Data on LARS derives nearly exclusively from rectal cancer studies. Therefore, the study was designed to assess LARS in advanced epithelial ovarian cancer (EOC) patients, who underwent rectal resection and to compare it with a female rectal cancer cohort.

Methods:

A cross-sectional multi-centre analysis was performed for female patients suffering from either rectal or EOC who received a low anterior resection as part of their therapy regimen. None of the patients received pre- or postoperative radiotherapy. LARS was defined by using the validated LARS score and its severity was divided into "no", "minor" and "major LARS".

Enrollment: 125 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• low anterior resection because of ovarian or rectal cancer

Exclusion criteria

• neoadjuvant or adjuvant radiotherapy

Trial design

125 participants in 2 patient groups

1

Description:

rectal cancer patients

Treatment:

Other: low anterior resection syndrome evaluation

2

Description:

ovarian cancer patients

Treatment:

Other: low anterior resection syndrome evaluation