Laryngomalacia No Longer An Ambiguity

Boushahri Clinic Medical Center

Status: Completed

Conditions: Laryngomalacia

Study type: Observational

Funder types: Other

Identifiers

NCT00972764

461956 (BoushahriCMC)

Details and patient eligibility

About

The purpose of this study is to expose some of the factors that may be associated or predisposing to development of laryngomalacia.

Full description

Laryngomalacia is the most common congenital malformation of the larynx and it is a self-limited disorder. It is the most common cause of stridor in newborns and infants. It results from an abnormal prolapse of supraglottic structures during inspiration. Despite its widespread prevalence, the etiology of laryngomalacia is unclear. Most infants will squeaky but otherwise well. Although affected patients do not exhibit much in the way of other physical symptoms, the unusual voice is worrisome to their parents.

Enrollment: 1,500 patients

Sex: All

Ages: 14 days to 2 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Babies delivered with laryngomalacia with ≥ 37 weeks of gestation
• Delivered with birth weights ≥ 2.5 kg
• No history of natal or post-natal complications
• From the same community

Exclusion criteria

• Pre-term babies
• History of natal or post-natal complications

Trial design

1,500 participants in 2 patient groups

Control

Laryngomalacia Cases