Laser-Assisted Versus Conventional Intracytoplasmic Sperm Injection

Shady Grove Fertility Reproductive Science Center

Status: Completed

Conditions: Infertility; Infertility, Male

Treatments: Procedure: Laser-assisted intracytoplasmic sperm injection

Study type: Interventional

Funder types: Other

Identifiers

NCT00114725

P2004-1

Details and patient eligibility

About

Laser-assisted intracytoplasmic sperm injection (ICSI) has been suggested as a more effective alterative to conventional ICSI when this method of insemination is indicated for patients undergoing in vitro fertilization (IVF). Laser-assisted ICSI differs from conventional ICSI in that a laser is used to drill a small hole through the hard outer coating surrounding an egg before the injection needle containing a single sperm is inserted into the egg. The hole eliminates compression of the egg that normally occurs with conventional ICSI, and thus may reduce the chance of damage. Laser-assisted ICSI is hypothesized to result in increased egg survival, and perhaps improved embryo quality, compared to conventional ICSI.

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of infertility
• Scheduled for IVF with ICSI

Exclusion criteria

• Retrieval of fewer than 6 mature oocytes

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)