Laser Meridian Massage in Heroin Addicts

Chang Gung Medical Foundation

Status: Unknown

Conditions: Heroin Dependence

Treatments: Device: laser meridian massage

Study type: Interventional

Funder types: Other

Identifiers

NCT04003077

PMRPG8J0081

M08G1056 (Other Grant/Funding Number)

201801823A3 (Other Identifier)

Details and patient eligibility

About

A case-controlled study is conducted to investigate the effect of adjuvant laser meridian massage in heroin addicts with methadone treatment and establish the model of laser meridian massage treatment for drug addiction.

Full description

Objective: To investigate the effect of adjuvant laser meridian massage in heroin addicts with methadone treatment and establish the model of laser meridian massage treatment for drug addiction.

Methods: A case-controlled study is conducted. Fifteen male heroin addicts are enrolled from Addiction Treatment Center as treatment group. They are treated with laser meridian massage on the back including Bladder meridian and Governor vessel three times a week for 4 weeks. A control group of participants without laser meridian massage treatment are matched by age. Check urine morphine before, 2 and 4 weeks of treatment. Subjects report their times or days of heroin use and self-fill Visual Analogue Scales of heroin craving / refusal of heroin use (0-10 points) during last week before, 2 and 4 weeks of treatment. Subjects report their quality of life using Short Form-12v2 before and 4 weeks of treatment. Obtain the subject's pulse diagnosis and heart rate variability after a single treatment. Independent t test, Mann-Whitney U test, chi-square test and Fisher's exact test were used to compare the differences between the treatment and control groups. Repeated measures ANOVA, Generalized estimating equations, paired t test and Wilcoxon Signed-Rank test were used for comparison between the treatment and control groups.

Enrollment: 30 estimated patients

Sex: Male

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Provide informed consent
• Male older than 20 years
• Diagnosed with opioid use disorder according to DSM-5 and received methadone treatment more than 1 month

Exclusion criteria

• Received Antidepressant or antipsychotic
• Received Chinese herb or acupuncture treatment during last 30 days
• Critical illness
• Did not meet the physician's assessment for recruitment
• Patients with Human immunodeficiency virus infection
• Did not provide informed consent

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

30 participants in 2 patient groups

Laser meridian massage

Experimental group

Description:

They are treated with laser meridian massage on the back including Bladder meridian and Governor vessel three times a week for 4 weeks.

Treatment:

Device: laser meridian massage

Control

No Intervention group

Description:

A control group of participants without laser meridian massage treatment are matched by age.