Laser Therapy for Patients With Systemic Lupus Erythematosus

Dr. Merve Benli

Status: Completed

Conditions: Chewing Function; Muscle Pain; Systemic Lupus Erythematosus

Treatments: Device: GaAlAs semiconductor diode laser device

Study type: Interventional

Funder types: Other

Identifiers

NCT04453215

1298

Details and patient eligibility

About

Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease that has detrimental effects on connective tissue and other organs. The musculoskeletal system is one of the most affected systems in this group of patients including the temporomandibular joint. The most common symptoms when muscle involvement in SLE are muscle atrophy decreased muscle strength and myopathy. SLE activity and long-term corticosteroid use are thought to be responsible for these symptoms, thus, SLE patients are accepted to be at higher risk for temporomandibular joint disorders (TMD). Low-level laser therapy(LLLT) is frequently used in the treatment of TMD due to its pain relief and anti-inflammatory effect. Thus, in this study, LLLT has been used to evaluate this treatment modality on the chewing function and pain values of SLE patients with myogenic TMD.

Enrollment: 91 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Having myogenic temporomandibular joint disorder,
• Following a stable medical regime,
• Showing minimum pain intensity of 50 mm on the visual analog scale.

Exclusion criteria

• Having concurrent systemic diseases,
• Using antimalarial drugs,
• Wearing removable prosthesis,
• History of facial trauma.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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91 participants in 3 patient groups, including a placebo group

test group

Experimental group

Description:

SLE patients treated with infrared laser irradiation

Treatment:

Device: GaAlAs semiconductor diode laser device

placebo group

Placebo Comparator group

Description:

SLE patients treated with red laser irradiation

Treatment:

Device: GaAlAs semiconductor diode laser device

control group

No Intervention group

Description:

no therapy group