Laser Therapy for Perioral Dermatitis

West Virginia University

Status: Withdrawn

Conditions: Perioral Dermatitis

Treatments: Drug: Clindamycin; Device: Pulse laser dye therapy (Device name: Candela Family of Pulsed Dye Laser Systems. 501k Number: K050673.)

Study type: Interventional

Funder types: Other

Identifiers

NCT03779295

1803028429

Details and patient eligibility

About

Perioral dermatitis is an inflammation of the skin around the mouth. The cause of perioral dermatitis is unknown. Current treatment methods include oral antibiotics and topical calcenurin inhibitors, both of which produce side effects and have been relatively ineffective in the treatment of perioral dermatitis. The investigators hope to assess the efficacy of laser therapy in treatment of perioral dermatitis by using laser therapy on one half of the patients face and having patients apply topical medication (clindamycin) to their face for 8 weeks. The side of their face that receives laser therapy will be randomized. The investigators will assess the efficacy of laser therapy by counting the number of lesions that patients have before and after laser therapy, comparing photos of patient's perioral dermatitis before and after treatment, and having patient's rate their satisfaction of the treatment.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age 18 years or older
• perioral dermatitis for greater than 1 month
• willing to return for follow-up visits 2 weeks, 4 weeks and 8 weeks following treatment.

Exclusion criteria

• skin type V or VI (due to risk of hyperpigmentation)
• pregnant
• breastfeeding
• unable to understand English
• mentally impaired
• incarcerated

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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0 participants in 2 patient groups

Pulse laser therapy

Experimental group

Description:

Pulse laser therapy will be randomly applied to right side or left side of face in addition to Clindamycin

Treatment:

Device: Pulse laser dye therapy (Device name: Candela Family of Pulsed Dye Laser Systems. 501k Number: K050673.)

Drug: Clindamycin

Clindamycin

Experimental group

Description:

Clindamycin only applied to side of face that does not receive pulse laser therapy.

Treatment:

Drug: Clindamycin