ClinicalTrials.Veeva

Menu

Laser Therapy on Orthodontic Tooth Movement

I

Ildeu Andrade Jr.

Status

Completed

Conditions

Orthodontic Tooth Movement
Bone Remodeling
Laser Therapy

Treatments

Device: Low-level Laser Therapy
Procedure: Orthodontic force

Study type

Interventional

Funder types

Other

Identifiers

NCT04070170
Laser on tooth movement

Details and patient eligibility

About

The aims of this study will be to evaluate if a Lower Level Laser Therapy (LLLT): (1) enhances the levels of important pro-inflammatory chemokines involved in the bone remodeling process; (2) increases the rate of orthodontic tooth movement (OTM) on human subjects.

Enrollment

24 patients

Sex

All

Ages

13 to 18 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Facial convexity
  • Protrusion or biprotrusion of the incisors
  • Dental crowding
  • Healthy periodontal condition
  • Satisfactory oral hygiene

Exclusion criteria

  • Patients under medications that may interfere with bone metabolism, such as anti-inflammatory, antibiotics and hormonal supplements in the previous three months
  • Skeletal crossbite
  • Parafunctional habits
  • Occlusal interference

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Quadruple Blind

24 participants in 5 patient groups

Low-level laser therapy and no orthodontic force
Experimental group
Description:
No orthodontic force. Laser is applied on the first day and the premolars is extracted after 24 hours
Treatment:
Device: Low-level Laser Therapy
Low-level laser therapy and application of orthodontic force
Experimental group
Description:
Orthodontic force and Laser is applied on the first day and the premolars is extracted after 24 hours
Treatment:
Procedure: Orthodontic force
Device: Low-level Laser Therapy
Orthodontic force only
Active Comparator group
Description:
Orthodontic force is applied and the premolars is extracted after 24 hours, with no laser therapy
Treatment:
Procedure: Orthodontic force
Low-level laser therapy and orthodontic force
Experimental group
Description:
Orthodontic force and Laser is applied and the orthodontic tooth movement is evaluated
Treatment:
Procedure: Orthodontic force
Device: Low-level Laser Therapy
Orthodontic force with no laser therapy
Active Comparator group
Description:
Orthodontic force is applied and the orthodontic tooth movement is evaluated, with no laser therapy
Treatment:
Procedure: Orthodontic force

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems