Lasers in Onychomycosis

Cairo University (CU)

Status: Not yet enrolling

Conditions: Onychomycosis

Treatments: Device: Laser

Study type: Interventional

Funder types: Other

Identifiers

NCT05415852

Lasers in onychomycosis

Details and patient eligibility

About

Onychomycosis is the most common nail disease, representing more than 50% of all onychopathies. Future studies on the absorption spectra of dermatophyte fungi will be needed to develop lasers that effectively exploit absorption differences in fungi and dermal tissue.

Full description

Treatments with antifungals may not be successful due to several factors, including the long time required to apply topical medications, the side effects of systemic drugs, and the application of insufficient medication to the target area. Even with adequate systemic or topical therapy, the persistence of fungal infections is not uncommon. In light of these limitations, laser therapy has been proposed as an alternative option for onychomycosis therapy.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with onychomycosis.

Exclusion criteria

• Patients with excessive manual work

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 4 patient groups

fractional CO2 laser

Active Comparator group

Description:

Laser

Treatment:

Device: Laser

Pulsed dye laser

Active Comparator group

Description:

Laser

Treatment:

Device: Laser

Nd Yag

Active Comparator group

Description:

Laser

Treatment:

Device: Laser

Q switched Nd Yag

Active Comparator group

Description:

Laser

Treatment:

Device: Laser