Lateral Postural Inclination in Parkinson's Disease : Involvement of the Basal Ganglia ? (IPOLAP)

Grenoble Alpes University Hospital Center (CHU)

Status

Terminated

Conditions

Parkinson Disease

Treatments

Behavioral: Subthalamic stimulation

Study type

Interventional

Funder types

Other

Identifiers

NCT02704910

1131

ID RCB (Other Identifier)

Details and patient eligibility

About

The objective of this study is to assess the origins of lateral postural inclination presented by some Parkinson disease's patients.

Several mechanisms could cause lateral postural inclination. Available data allow to suggest three hypothesis: (troubles of tonus, perception of vertical perturbation, trouble of perception of corporal axis

Full description

Inclusion Criteria:

30 to 75 years old patient
Parkinson disease's diagnosed since 5 years
Treated by deep brain stimulation
Patient with at least 6 degree lateral deviation
Without vestibular troubles nor peripheral sensorial trouble.

Exclusion Criteria:

Dementia (Mattis < 130 ou MMS <24), or severe depressive episode according to DSM IV-R criteria
Camptocormia or incompatible anteflexion with the dispositive of measure device
Pregnant woman, nursing mother

Enrollment

38 patients

Sex

All

Ages

30 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

30 to 75 years old patient
Parkinson disease's diagnosed since 5 years
Treated by deep brain stimulation
Patient with at least 6 degree lateral deviation
Without vestibular troubles nor peripheral sensorial trouble.

Exclusion criteria

Dementia (Mattis < 130 ou MMS <24), or severe depressive episode according to DSM IV-R criteria
Camptocormia or incompatible anteflexion with the dispositive of measure device
Pregnant woman, nursing mother