Leber Hereditary Optic Neuropathy (LHON) Historical Case Record Survey

Santhera

Status: Completed

Conditions: Leber Hereditary Optic Neuropathy (LHON)

Study type: Observational

Funder types: NETWORK; Industry

Identifiers

NCT01892943

LHON HCR

Details and patient eligibility

About

The objective of this survey is to establish the clinical course of vision loss and recovery in patients with a genetically confirmed diagnosis of Leber Hereditary Optic Neuropathy (LHON).

Visual acuity changes over time from onset of symptoms and from visual acuity nadir will be the main endpoint analysed.

The survey will collect historically documented visual acuity data for all patients at participating sites with a genetically confirmed diagnosis of LHON. No exclusion criteria apply. Patients are not required to attend the clinic for the survey.

Data will be collected in a completely anonymous manner. Ethical approvals and data release agreements will be obtained as required by local regulations.

Enrollment: 306 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• patients with genetically confirmed diagnosis of LHON

Trial design

306 participants in 1 patient group

Patients with LHON