Left Atrial Appendage Occlusion in Patients With Non-valvular Atrial Fibrillation From Shanghai (LAAO-SH)

Tongji University

Status: Unknown

Conditions: Left Atrial Appendage Occlusion; Atrial Fibrillation

Treatments: Device: left atrial appendage occlusion devices

Study type: Observational

Funder types: Other

Identifiers

NCT03987945

LAAO-SH

Details and patient eligibility

About

The prognostic implication of left atrial appendage occlusion (LAAO) procedure in non-valvular atrial fibrillation (NVAF) patients from China is still unclear. We aim to investigate the impact of LAAO procedure on subsequent clinical outcomes in patients from China.

Full description

Although the left atrial appendage occlusion (LAAO) procedure has increasingly been performed to prevent the occurrence of ischemic stroke events among patients with non-valvular atrial fibrillation (NVAF), the clinical benefits and prognostic implications of which have not been well characterized in patients from China. As a result, we aim to conduct an observational study to explore the prognostic impact of LAAO in patient with NVAF who are hospitalized in Shanghai Tenth People's Hospital.

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who were admitted for NVAF undergoing LAAO procedure between January 2014 and December 2017 in the Cardiology Department of Shanghai Tenth People's Hospital;
• Adult patients (>18 years old).

Exclusion criteria

• Patients with rheumatic valvular disease;
• Patients with sick sinus syndrome;
• Patients who had a history of cardiac surgery (i.e., CABG);
• patients who had received the catheter radiofrequency ablation procedure.

Trial design

150 participants in 1 patient group

Left atrial appendage occlusion

Description:

Patients with non-valvular atrial fibrillation who have received left atrial appendage occlusion procedure.

Treatment:

Device: left atrial appendage occlusion devices