Left Atrium Substrate Based Ablation Plus Circumferential Pulmonary Vein Isolation to Treat Chronic Atrial Fibrillation

Nanjing Medical University

Status: Unknown

Conditions: Atrial Fibrillation

Treatments: Procedure: radiofrequency catheter ablation

Study type: Interventional

Funder types: Other

Identifiers

NCT01716143

2011-SR-014

Details and patient eligibility

About

The purpose of this study is to determine whether left atrium substrate based ablation plus circumferential is effective in the treatment of persistent and long-standing atrial fibrillation.

Enrollment: 87 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

All persistent or permanent AF patients with refractory or intolerant to at least one Class 1 or Class 3 antiarrhythmic medication.

Exclusion criteria

1. Patients with paroxysmal AF (self-terminating episodes lasting < 7 day)
2. Patients who have had a previous AF ablation procedure
3. Pregnancy

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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87 participants in 1 patient group

catheter ablation

Other group

Treatment:

Procedure: radiofrequency catheter ablation