Left Bundle Branch Block (LBBB) After IntuityTM

Public Assistance-Hospitals of Marseille (AP-HM)

Status: Completed

Conditions: Aortic Valve Disease

Study type: Observational

Funder types: Other

Identifiers

NCT04897659

CIL 2019-48 bis

Details and patient eligibility

About

This study aimed to evaluate incidence, prognosis and predictive factors of new-onset of persistent left bundle branch block (LBBB) after rapid-deployment aortic valve replacement (RD-AVR) with the IntuityTM bioprosthesis.

It was an observational, retrospective and single-center study. Two hundred and seventy-four consecutive patients without any baseline ventricular conduction disorder or previous permanent pacemaker or defibrillator implantation who underwent RD-AVR with the IntuityTM valve were included. Twelve-lead electrocardiogram and transthoracic echocardiography were performed preoperatively, postoperatively, at discharge, 1-month, and 1-year. Incidence, prognosis and predictive factors of new-onset of persistent LBBB were evaluated.

Enrollment: 274 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• rapid-deployment aortic valve replacement (RD-AVR) with the Edwards Intuity™ bioprosthesis for severe aortic valve stenosis
• between July 2012 and May 2018

Exclusion criteria

• preoperative permanent pacemaker or defibrillator,
• complete intraventricular conductive disorder defined by a QRS width ≥ 120 ms.
• absence of patient's authorization for anonymous publication of their clinical data for research purposes.