Left Elective Colectomy in Renal Transplanted Patients (LECoRT)

University Hospital Center (CHU)

Status: Completed

Conditions: Renal Transplanted Patients; Left Elective Colectomy

Treatments: Procedure: Left elective colectomy

Study type: Observational

Funder types: Other

Identifiers

NCT04495023

RECHMPL20_0356

Details and patient eligibility

About

Aim of the study :

To evaluate postoperative outcomes of elective left-sided colectomy in a renal transplanted population.

Methods :

From 2010 to 2015, all consecutive patients who underwent left elective colectomy in a referral center were prospectively collected.

Considering our exclusion criterial, data from 120 patients were analyzed. The cohort was separated into 2 groups : renal transplanted patients (KTR-group) and non-renal transplanted patients (C-group) Short and longterm outcomes were compared between the two groups.

Primary outcome :

90 days postoperative anastomotic leak rate

Full description

From January 2010 to December 2015, data from patients requiring an elective left colectomy for benign or malignant indication were collected prospectively in our colorectal surgery database.

According to our exclusion criterial patients were retrospectively divided into two groups: kidney transplant recipients (KTR-group) and control group (C-group).

The surgical indication for an oncologic left colectomy was retained by the expert surgeon, after a multidisciplinary conversation meeting comprising at least one surgeon, one gastroenterologist, one nephrologist, one radiologist and one oncologist. The surgical indication for diverticular disease was based on French guidelines.

Demographic, clinical, intraoperative and postoperative, histological, length of hospital stay and mortality data were collected over a 90-day period following the intervention.

Enrollment: 120 patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Open or laparoscopic left elective colectomy with colo-rectal anastomosis
• age > 18 y.o.

Exclusion criteria

• emergency surgery
• past history of rectal surgery
• ASA I

Trial design

120 participants in 2 patient groups

Group 1 (Kidney transplanted patients)

Description:

Group 1: Kidney transplanted patients requiring oncologic or non-oncologic left elective colectomy All kidney transplanted patients requiring oncologic or non-oncologic left elective colectomy between 01 January 2004 and 31 December 2015.

Treatment:

Procedure: Left elective colectomy

Group 2 (Non-transplanted patients)

Description:

Group 2 : Non-transplanted patients requiring oncologic or non-oncologic left elective colectomy Non-transplanted patients requiring oncologic or non-oncologic left elective colectomy between 01 January 2004 and 31 December 2015.

Treatment:

Procedure: Left elective colectomy