Left Ventricular Dysfunction in Critically Ill Patients (LEVEDYCIP)

Sahlgrenska University Hospital

Status: Completed

Conditions: Acute Coronary Syndrome; Critically Ill; Cardiomyopathies; Left Ventricular Dysfunction; Takotsubo Cardiomyopathy

Treatments: Diagnostic Test: Echocardiography

Study type: Observational

Funder types: Other

Identifiers

NCT03787810

LEVEDYCIP

Details and patient eligibility

About

Left ventricular dysfunction is common in the critically ill. The aim of this study is to assess the incidence and prognosis of left ventricular dysfunction in critically ill patients.

Full description

Left ventricular dysfunction is common in the critically ill. A number of conditions can cause left ventricular dysfunction including myocardial infarction, septic cardiomyopathy, post resuscitation syndrome, takotsubo syndrome etc. A number of studies have assessed cardiac dysfunction in specific conditions (e.g. sepsis, cardiac arrest) but only a few studies have assessed cardiac dysfunction in a general ICU-population. The study will focus on diagnostics of the different types of cardiomyopathy and differentiating between ischemic and non-ischemic left ventricular dysfunction in a general ICU population. The aim of this study is to assess the incidence and prognosis of the different types of left ventricular dysfunction in critically ill patients. Our hypothesis is that left ventricular dysfunction is common in the critically ill and is associated with an increased risk of short-term death.

Enrollment: 428 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Admitted within 24 hours to the ICU
• Dysfunction of at least one organ system, defined as at least +1 point in SOFA-score.

Exclusion Criteria