Leg Exercise During ECMO

University of Minnesota (UMN)

Status: Completed

Conditions: Refractory Respiratory Failure

Treatments: Device: Closed-Chain Leg Exercise; Other: Open-Chain Leg Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT03135210

1703M10081

Details and patient eligibility

About

Patients undergoing extracorporeal membrane oxygenation (ECMO) are at high risk for deconditioning and functional decline. The primary aim of this study is to assess the functional impact of leg exercise during the pre-ambulation phase in patients undergoing ECMO.

Full description

The investigators are conducting this study to explore the impact of closed-chain leg exercise in individuals undergoing ECMO.

Aim 1: To determine if closed-chain leg exercise decreases the time to initial ambulation. The investgators hypothesize that adding leg exercise will decrease time to ambulation.

Aim 2: To determine the impact of closed chain leg exercise on functional ability. The investigators hypothesize that adding leg exercise will improve functional outcomes when added to an existing early mobilization program.

Aim 3: To determine the effect of closed chain leg exercise on hospital outcomes. The investigators hypothesize that hospital related outcomes will improve when leg exercise is added to an existing early mobilization program.

Enrollment: 4 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with refractory respiratory failure undergoing ECMO at the University of Minnesota Medical Center, Fairview.
• Able to follow 3 out of 3 one-step commands via protocol.
• Active Inpatient Physical Therapy Referral.
• ECMO delivery is veno-venous with internal jugular catheter.

Exclusion criteria

• Femoral catheter of any kind present
• Veno-arterial ECMO set-up
• Sedation such that self-consent is not attainable
• Medical instability, as determined by primary critical care physician

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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4 participants in 2 patient groups

Open-Chain Leg Exercise

Active Comparator group

Description:

Individuals in the open-chain group will progress through standard mobility progression.

Treatment:

Other: Open-Chain Leg Exercise

Closed-Chain Leg Exercise

Experimental group

Description:

Individuals in the closed-chain group will progress through standard mobility exercises with the addition of closed-chain leg exercises using the MOVEO platform.

Treatment:

Device: Closed-Chain Leg Exercise