Lemon Verbena Extract Oxidative Stress and Muscle Damage

National Taiwan Sport University

Status: Completed

Conditions: Muscle Injury; Muscle Soreness

Treatments: Dietary Supplement: Lvemon verbena extract; Dietary Supplement: maltodextrin

Study type: Interventional

Funder types: Other

Identifiers

NCT04742244

00002

Details and patient eligibility

About

In the present study, investigators investigated whether supplementation with lemon verbena extract (LVE) could improve muscle damage and biochemical indicators after exhaustive exercise challenge. Based on maximum jump heights, 60 subjects (30 males and 30 females) were equally divided into a placebo group (0 mg/human/day) and an LVE supplement group (400 mg/human/day), with gender-equal distribution. All subjects started supplementation 10 days before exhaustive exercise and continued it until all tests were completed. Before the intervention, after the exhaustive exercise, and on the following 3 days, the participants underwent 12-minute Cooper running/walking; blood collection; assessments of pain, muscle stiffness, maximum jump heights, and isometric maximum muscle strength; and anaerobic strength tests.

Enrollment: 60 patients

Sex: All

Ages: 20 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• health
• Must be able to swallow tablets

Exclusion criteria

• non-smokers
• no musculoskeletal
• medical
• metabolic disease
• women not on the reproductive cycle
• high blood pressure, asthma
• skeletal neuromuscular injuries in the upper or lower extremities

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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60 participants in 2 patient groups, including a placebo group

Placebo

Placebo Comparator group

Description:

0 mg LVE/capsule, 2capsule/day, 14days

Treatment:

Dietary Supplement: maltodextrin

Lemon Verbena extract

Experimental group

Description:

200 mg LVE/capsule, 2capsule/day, 14days

Treatment:

Dietary Supplement: Lvemon verbena extract