Leptin Signaling in Lean and Obese Humans (Leptin signali)

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VA Office of Research and Development

Status

Withdrawn

Conditions

Obesity

Study type

Observational

Funder types

Other U.S. Federal agency

Identifiers

NCT01297426
ENDA-013-10F

Details and patient eligibility

About

Obesity does not respond to high circulating levels of the hormone leptin. This study is aiming at finding out why this happens and open new avenues for treatment of obesity.

Full description

Ex vivo and in vitro identification and study of leptin signaling pathways in commercially available cell lines serum/ plasma samples and discarded tissues from humans.

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • men and women
  • ages 18 to 65
  • BMI ranges between 20 and 45 kg/m2

Exclusion criteria

  • subjects requiring special diets
  • history of illness other than obesity of diabetes
  • taking medications known to influence glucose metabolism
  • subjects with history of anaphylactic reaction or hypersensitivity to e. coli derived proteins or anesthetic agents
  • women who are breastfeeding, pregnant or wanting to become pregnant
  • subjects with bleeding dyscrasia or poor wound healing

Trial design

0 participants in 1 patient group

Group 1
Description:
Lean and obese, diabetic and non diabetics

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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