Leucine Supplementation in Young Subjects Undergoing Resistance Training

University of Sao Paulo

Status: Completed

Conditions: Healthy Volunteers

Treatments: Dietary Supplement: Leucine; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT02744443

LeucineUSP

Details and patient eligibility

About

Leucine supplementation could be useful to support muscle anabolism. This study aims to investigate the effects of leucine supplementation on muscle mass and muscle strength in young subjects undergoing resistance training.

Enrollment: 60 patients

Sex: Male

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• training experience > 12 months
• no previous use of anabolic steroids
• no diagnosed diseases or injuries at the time of recruitment
• one-maximum repetition strength (1-RM) in leg press ≥ 3.5 and ≤ 5.0 times the body weight

Exclusion criteria

• use of creatine or beta-alanine supplements for the last 3 months
• use of protein or aminoacids supplements for the last 1 month
• engagement in specific dietary restrictions
• engagement in competitive sports

Trial design

60 participants in 2 patient groups, including a placebo group

Leucine

Experimental group

Description:

Leucine supplementation (10 g/d)

Treatment:

Dietary Supplement: Leucine

Placebo

Placebo Comparator group

Description:

Placebo supplementation (alanine, 10 g/d)

Treatment:

Dietary Supplement: Placebo