Level of Middle Cranial Fossa Dura in Patients With Cholesteatoma

Assiut University

Status: Unknown

Conditions: Cholesteatoma, Middle Ear

Treatments: Radiation: Multislice computed tomography temporal bone

Study type: Observational

Funder types: Other

Identifiers

NCT04551612

Patients with Cholesteatoma

Details and patient eligibility

About

Cholesteatoma is a destructive lesion that progressively expands in the middle ear, mastoid or petrous bone and leads to destruction of the nearby structures. Erosion, which is caused by bone resorption of the ossicular chain and otic capsule, may cause hearing loss, vestibular dysfunction, facial paralysis and intracranial manifestations

Full description

Cholesteatoma has three Classical forms: (1) Congenital, primary or genuine cholesteatoma: occurs behind an intact tympanic membrane. Primary acquired cholesteatoma: looks like a limited diverticulum of the pars flaccida with little or no history of otorrhea. Secondary acquired cholesteatoma: develops with posterosuperior perforations in eardrum and expansion of the disease process into the antrum, mastoid, attic and middle ear. Granulation tissue, polyps and foul- smelling otorrhea are common findings in this type

Enrollment: 80 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All adults above the age of 18 presented to the Assiut university Clinic with

cholesteatoma will be included in the study.

Exclusion criteria

1. Patients with previous mastoid surgery
2. Patients with Craniofacial anomalies or cleft lip and palate
3. Pediatric populations ≤ 18 years old
4. Patients with congenital ear anomalies

Trial design

80 participants in 1 patient group

Patients with cholesteatoma

Description:

Patients with cholesteatoma in one ear that will compared with the other healthy one.

Treatment:

Radiation: Multislice computed tomography temporal bone