Levels of Circulating T Cells Expressing VLA-1 Collagen Receptors

Sheba Medical Center

Status: Completed

Conditions: Ischemic Heart Disease

Study type: Observational

Funder types: Other

Identifiers

NCT00708838

SHEBA-02-2707-AA-CTIL

Details and patient eligibility

About

The examination of the percentage of peripheral T cells carrying VLA-1 in ischemic heart disease patients. The hypothesis is that the percentage levels of cells carrying this integrin rise according to the severity of the ischemic heart disease.

Full description

Atherosclerosis is considered an inflammatory disease in which lymphocytes have an important role. The study was disigned to find out the changes in T cell levels carrying VLA-1 involvement in this process.

Enrollment: 151 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• clinical diagnosis of acute MI for group 1
• clinical diagnosis of ACSl for group 2
• clinical diagnosis of Chronic Heart Disease for groups 3 and 4
• Chest pain but normal heart scan for group 5

Exclusion criteria

• none

Trial design

151 participants in 5 patient groups

1

2

3

4

5