Levels of High-Sensitivity C-Reactive Protein in Heart Transplant Patients

Baskent University

Status: Completed

Conditions: Periodontitis; Crp; Heart Transplant Failure

Treatments: Other: clinical measurements

Study type: Observational

Funder types: Other

Identifiers

NCT03671408

BaskentU3

Details and patient eligibility

About

Objectives: The outcomes of heart transplantation are very favorable but inflammation still plays a critical role in deterioration of chronic transplants. Periodontal diseases are not only limited to supporting structures of the teeth, they also cause systemic inflammation. Based on the importance of inflammation in heart transplant recipients and the association between periodontal disease and systemic inflammation, this study explored whether periodontitis may be a modifier of serum high-sensitivity C-reactive protein (HsCRP) in heart transplant patients.

Enrollment: 33 patients

Sex: All

Ages: 11 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

be clinically stable be at least 1 year post-transplant; no history of antibiotic use during the preceding 4 months have had no periodontal treatment within the previous year.

Exclusion criteria

having other systemic infections

Trial design

33 participants in 2 patient groups

periodontitis

Description:

periodontitis patients which were diagnosed based on clinical parameters

Treatment:

Other: clinical measurements

gingivitis/healthy

Description:

gingivitis healthy patients which were diagnosed based on clinical parameters

Treatment:

Other: clinical measurements