Levetiracetam Versus Valproate in Idiopathic Generalized Epilepsy (LEVAGE)

Mazandaran University of Medical Sciences

Status: Completed

Conditions: Treatment of Idiopathic Generalized Epilepsy

Treatments: Drug: Levetiracetam; Drug: Sodium valproate

Study type: Observational

Funder types: Other

Identifiers

NCT06393309

14751

Details and patient eligibility

About

This study aimed to compare the long-term efficacy and safety of levetiracetam and valproate in treatment of idiopathic generalized epilepsy.

Enrollment: 169 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of juvenile myoclonic epilepsy or generalized tonic-clonic seizure alone
• Regular monotherapy with levetiracetam or sodium valproate

Exclusion criteria

• Poor drug adherence
• Pregnancy

Trial design

169 participants in 2 patient groups

Levetiracetam

Description:

Patients with idiopathic generalized epilepsy who were under treatment with levetiracetam

Treatment:

Drug: Levetiracetam

Sodium valproate

Description:

Patients with idiopathic generalized epilepsy who were under treatment with valproate

Treatment:

Drug: Sodium valproate