Levosimendan Versus Dobutamine in Cardiopatic Patients Undergoing Major Non Cardiac Surgery

Azienda Policlinico Umberto I

Status and phase: Unknown; Phase 4

Conditions: Cardiovascular Diseases

Treatments: Drug: Levosimendan; Drug: Dobutamine

Study type: Interventional

Funder types: Other

Identifiers

NCT02012946

levodobu

Details and patient eligibility

About

This study wants to investigate the hemodynamic changes in cardiopatic patients undergoing major non cardiac surgery, during and after the continuous infusion of levosimendan or dobutamine.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• EF < 40%, no liver and renal disfynction, chronic cardiopathy

Exclusion criteria

• acute coronary syndrome, life expectation <30 days, hemodialysis, ventricular tachycardia/ventricular fibrillation

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

40 participants in 2 patient groups

dobutamine

Active Comparator group

Description:

patient receiving dobutamine

Treatment:

Drug: Dobutamine

Levosimendan

Active Comparator group

Description:

patient receiving levosimendan

Treatment:

Drug: Levosimendan