LHC-CIDI-5 in Hong Kong

The University of Hong Kong (HKU)

Status: Enrolling

Conditions: Bipolar Sub Disorder; Alcohol Use Disorder (AUD); Panic Attack; Hypomanic; Suicidal Attempt; PCL-SC PTSD; Suicidal Plan; Major Depressive Episode (MDE); Substance Use Disorder (SUD); PCL-5 PTSD; Posttraumatic Stress Disorder (PTSD); Nonsuicidal Self-Injury; Obsessive-Compulsive Disorder (OCD); Persistent Depressive Disorder (PDD); Bipolar II Disorder; Suicidal Ideation; Panic Disorder; Bipolar I Disorder; Intermittent Explosive Disorder (IED); Manic Episode; Suicidal Gesture; Generalized Anxiety Disorder (GAD); Major Depressive Disorder (MDD)

Treatments: Diagnostic Test: LHC-CIDI-5; Diagnostic Test: CIDI-5

Study type: Observational

Funder types: Other

Identifiers

NCT06804525

UW 24-771

2024-0089-004 (Other Grant/Funding Number)

Details and patient eligibility

About

The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12 months, and lifetime) based on the diagnostic criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) and International Classification of Diseases 10th edition (ICD-10). However, retrospective measurements like the CIDI-5 are susceptible to recall bias, especially for the lifetime experience, which can hinder the reporting accuracy with mental disorders.

To mitigate this issue, the life history calendar (LHC) was introduced as an aid to assist respondents in recalling the timing of life events, enhancing the ability of the CIDI-5 to measure the lifetime prevalence of mental disorders. The LHC is a grid structure with columns representing time units and rows representing life domains under study.

In a study conducted in Nepal, combining the CIDI-5 with the LHC resulted in a significant increase in the detection of mental disorders compared to using the CIDI-5 alone. This approach did not lead to an increase in false positives after clinical validation.

This experiment aims to adapt a Hong Kong version of the LHC based on the Nepalese model and evaluate the effectiveness of the LHC-assisted CIDI-5 (LHC-CIDI-5) compared to the CIDI-5 alone in assessing mental disorders.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 25+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All household members aged 25 years old and over are randomly sampled from the Census and Statistics Department List of Quarters
• Live in the address sampled from the Census and Statistics Department List of Quarters
• Reside in Hong Kong for at least six months in the past year
• Able to read and communicate in Chinese or English
• Without linguistic or cognitive difficulties

Exclusion criteria

• Domestic workers

Trial design

1,000 participants in 2 patient groups

CIDI-5

Description:

For the CIDI-5 group, respondents will directly partake in the CIDI-5 interview without responding to any inquiries regarding their life history.

Treatment:

Diagnostic Test: CIDI-5

LHC-CIDI-5

Description:

For the LHC-CIDI-5 group, respondents, before initiating the CIDI-5, will begin with LHC, completing a calendar by answering questions about important personal experiences since birth until the interview year.

Treatment:

Diagnostic Test: LHC-CIDI-5