Licorice and Home Blood Pressure, Additional Study

Linköping University (LiU)

Status

Completed

Conditions

Hypertension,Essential

Treatments

Other: Licorice

Study type

Interventional

Funder types

Other

Identifiers

NCT06019598

licorice2023_additional

Details and patient eligibility

About

Out-of-office blood pressure is more strongly associated with cardiovascular risk than office blood pressure. Licorice is known to raise blood pressure, but no previous studies have measured the effects on home blood pressure. The aim of this study is to analyze the association between licorice intake and home blood pressure.

Full description

For a detailed background, please see Clinical Trials registration number NCT05661721. In brief, out-of-office blood pressure is more strongly associated with cardiovascular risk than office blood pressure. Licorice is known to raise blood pressure, but no previous studies have measured the effects on home blood pressure. In a previous study, the response to licorice intake varied between participants. The aim of this study is to analyze the response of the most "licorice sensitive" quartile of participants from the original study to lower dosages of licorice, corresponding to 20 and 50 milligram och GA daily.

Enrollment

3 patients

Sex

All

Ages

18 to 31 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Previous participation in the Licorice and home blood pressure study (NCT05661721).

Exclusion criteria

Known hypertension, cardiovascular disease, kidney disease, liver disease, hormonal disease, peanut allergy, eating disorder or headache disease (including tension headache and migraine)
Known alcohol abuse or drug abuse (including cannabis and anabolic steroids) treatment with hormonal drugs (including oral contraceptives
Known intolerance to licorice intake.