Lidocaine 5% Patch Supplementation to Intra-articular Bupivacaine Dexmedetomidine After Arthroscopic Knee Surgery

Tanta University

Status: Completed

Conditions: Arthroscopic Knee Surgery; Dexmedetomidine; Intra-articular; Lidocaine 5% Patch

Treatments: Drug: Lidocaine 5% patch with Dexmedetomidine Bupivacaine; Drug: Dexmedetomidine Bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT04322760

31084/07/16

Details and patient eligibility

About

Surgery of the knee is a very common procedure which can be very painful and sufficient postoperative pain treatment is often problematic. The aim of this work was to study the effects of supplementation of intra-articular bupivacaine dexmedetomidine with lidocaine 5% patch after arthroscopic knee surgery under general anesthesia and its role in improving quality of anesthesia.

Enrollment: 40 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients
• ASA I & II
• Aged between 18 to 60 years
• Weight between 60 to 100 kg
• Scheduled for elective arthroscopic knee surgery

Exclusion criteria

• patient refusal.
• history of cardiac disease.
• impaired renal or hepatic function.
• hypertension treated with α methyldopa, clonidine, or beta-adrenergic blockers.
• if they have used opioid analgesics within the previous 24 hr.
• previous sensitivity to local anesthetics.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Group A (control group)

Active Comparator group

Description:

Patients in each received 10 ml 0.5 % bupivacaine and 1µg/kg dexmedetomidine diluted in 10 ml saline injected intra-articularly without lidocaine patch

Treatment:

Drug: Dexmedetomidine Bupivacaine

Group B

Experimental group

Description:

Patients in each received 10 ml 0.5 % bupivacaine and 1µg/kg dexmedetomidine diluted in 10 ml saline injected intra-articularly with a patch of lidocaine 5% was applied to the skin

Treatment:

Drug: Lidocaine 5% patch with Dexmedetomidine Bupivacaine