Lidocaine Spray for Pain Control in Rib Fractures

Ankara City Hospital

Status and phase: Completed; Phase 4

Conditions: Analgesia; Rib Fractures

Treatments: Drug: Lidocaine topical

Study type: Interventional

Funder types: Other

Identifier

NCT05500677

Details and patient eligibility

About

In this study, we aimed to compare the analgesic efficacy of lidocaine spray with tramadol hydrochloride and fentanyl citrate in rib fractures.

Full description

Patients over the age of 18 who came to our emergency department with blunt chest trauma were divided into three groups. Groups was created from patients who were given lidocaine 10% spray (local), i.v. 100 mg of tramadol and i.v. fentanyl 50 mcg. A total of 48 patients, each of whom were 16, were included in the study. Numerical rating scale (NRS) pain scores of the patients at baseline, 15th, 30th and 60th minutes were compared. These scores and the amount of falls at follow-up were analyzed comparatively between the 3 groups.

Enrollment: 48 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Open conscious
• Oriented and cooperative
• Blunt thoracic trauma and rib fracture
• Numerical rating scale (NRS) was 5 or higher

Exclusion criteria

• Patients who refused to participate in the study
• Detected or suspected pregnancy
• Known history of allergy or other adverse reaction to the drugs used in the study
• History of sedative drug use or drug addiction
• Analgesic use within 6 hours of admission to the emergency department
• Needed emergency tube thoracostomy or surgical intervention
• Hemodynamically unstable
• Open and/or infected wounds in the fracture area

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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48 participants in 3 patient groups

Lidocaine

Active Comparator group

Description:

10% lidocaine spray was applied on the broken rib from a distance of 10 cm, 1-2 puffs. Each puff contains 10 mg of lidocaine.

Treatment:

Drug: Lidocaine topical

Tramadol

Active Comparator group

Description:

100 mg of tramadol hydrochloride was placed in 150 cc isotonic saline and given as a 15-minute intravenous infusion.

Treatment:

Drug: Lidocaine topical

Fentanyl

Active Comparator group

Description:

50 mcg of fentanyl citrate was given as a 15-minute intravenous infusion in 150 cc isotonic.

Treatment:

Drug: Lidocaine topical