Life Quality and Health in Patients With Klinefelter Syndrome

University of Aarhus

Status: Completed

Conditions: Klinefelter Syndrome; Mental Disorders; Physical Disorders; Quality of Life

Study type: Observational

Funder types: Other

Identifiers

NCT01690013

2012-41-0666

Details and patient eligibility

About

Klinefelter syndrome is the most common sex-chromosome disorder in men with a prevalence of 1 in 660 men. The syndrome is associated with hypogonadism. Many patients with Klinefelter syndrome have psychological complaints and physical discomfort. Some patients report a positive effect of testosterone treatment, whereas others do not.

The aim of this study is:

(i) To investigate quality of life in patients with Klinefelter syndrome. (ii) To investigate functional, physical and mental health in patients with Klinefelter syndrome.

Questionnaire concerning mental and physical health and life quality are sent out to patients with KS and to age-, educational- and zipcode-matched men from the general population. The questionnaire include questions about housing, income, marital status, fatherhood, medication, chronic disease,school and education, attachment to the labor, sexual and erectile function, life quality, mental and physical health, satisfaction with life and symptoms of attention deficits hyperactivity disorders.

Enrollment: 452 patients

Sex: Male

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

For the Klinefelter group:

Inclusion Criteria:

• Verified Klinefelter syndrome

Exclusion Criteria:

• none

For the control group:

Inclusion Criteria:

• age-,educational,and residence-matched

Exclusion Criteria:

• none

Trial design

452 participants in 2 patient groups

Klinefelter

Description:

Men with Klinefelter syndrome

Control

Description:

Men from the general population, matched by age, education and zipcode.