Lifestyle, Fitness, and Plasma Biomarkers in Healthy Young Adults (NEUROACTIVE)

European University Miguel de Cervantes

Status: Enrolling

Conditions: Healthy Young Adults

Study type: Observational

Funder types: Other

Identifiers

NCT07032168

PI-DOC010-NEUROACTIVE

Details and patient eligibility

About

Lifestyle play a key role in modulating brain health by directly influencing a number of key biological processes, such as neuroplasticity, neurogenesis, and regulation of biomarkers associated with cognitive decline. Factors such as physical activity, diet, sleep quality, stress management, and body composition have been shown to have a significant impact on neuroprotection and cognitive performance. These factors not only contribute to maintaining metabolic and functional balance in the body, but are also linked to the expression of biomarkers such as brain-derived neurotrophic factor (BDNF) and Tau protein phosphorylated at the amino acid threonine 217 (PTau217), which are essential for the maintenance of neuronal health and the prevention of neurodegenerative diseases. In this sense, a healthy lifestyle, characterized by regular physical activity, a balanced diet, good quality sleep, low stress levels and adequate body composition, can act as a protective factor against cognitive decline from early stages of life.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 24 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

The following inclusion criteria are established:

1. Age between 18 and 24 years.
2. Not have chronic or neurodegenerative diseases.
3. Not be on pharmacological treatment that affects the central nervous system or metabolism.

The exclusion criteria for participants:

1. Medical or traumatological condition that makes it impossible to practice physical exercise.
2. Musculoskeletal injury within 6 months prior to the first visit to the laboratory.
3. Recent surgery (<3 months).
4. Have a medical condition in which physical activity is contraindicated (assessed with the Physical Activity Predisposition Questionnaire (PARQ+).

Trial design

30 participants in 1 patient group

Healthy young adults

Description:

Healthy young adults (18-24 years old)