Lifestyle Interventions to Reduce Diabetes Risk

National Institutes of Health (NIH)

Status: Completed

Conditions: Diabetes Mellitus, Type 2; Glucose Intolerance

Treatments: Behavioral: exercise and diet

Study type: Interventional

Funder types: NIH

Identifiers

NCT00006162

fujimotow (completed)

1R01DK048152 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

Type 2 diabetes is more frequent in Japanese Americans than in Japan or the U.S. non-Hispanic white population. This appears to be due to the effects of ''westernization'' to bring out metabolic changes that lead to diabetes. This study will look at whether increased physical activity and dietary changes will reduce or prevent the metabolic changes that lead to type 2 diabetes in Japanese Americans who have impaired glucose tolerance, a condition intermediate between normal glucose tolerance and diabetes.

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Japanese American
• Confirmed impaired glucose tolerance
• Able to fill out questionnaires

Exclusion criteria

• Significant exercise-restricting disease
• Poorly controlled hypertension
• Psychiatric disease or dementia
• Already on unusually restrictive diet
• Use of hypolipidemic drugs
• Use of tobacco
• Abnormal blood screening tests
• ECG evidence of ischemic heart disease at rest
• Abnormal maximal Bruce treadmill test