Lifestyle Modification and Potato Consumption

USDA Grand Forks Human Nutrition Research Center

Status: Completed

Conditions: Obesity

Treatments: Other: other carbohydrate; Other: potatoes

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT01771926

GFHNRC024

Details and patient eligibility

About

The investigators hypothesize that consumption of potatoes is a healthy adjunct to lifestyle intervention in overweight and obese glucose intolerant adults. We will evaluate the effects of the consumption of potatoes (high or low resistant starch) vs. commonly consumed carbohydrate sources on glucose tolerance; and ( the extent to which potato consumption alters markers of lipid metabolism and inflammation in the context of a lifestyle intervention program.

Full description

Our primary objective is to compare the effects of potato consumption to those of commonly consumed carbohydrate sources on glucose tolerance and other cardiometabolic risk factors in overweight and obese, glucose intolerant men and women participating in a lifestyle intervention program. We hypothesize that consumption of potatoes is a healthy adjunct to lifestyle intervention in overweight and obese glucose intolerant adults. Our specific aims include: (1) to evaluate of the effects of the consumption of potatoes (high or low resistant starch) vs. commonly consumed carbohydrate sources on glucose tolerance; and (2) to determine the extent to which potato consumption alters markers of lipid metabolism and inflammation in the context of a lifestyle intervention program.

Enrollment: 107 patients

Sex: All

Ages: 20 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Men and women between 20-65 years of age.
• Overweight or obese (BMI 25 - 39.9 Kg/m2)
• Impaired Glucose Tolerance: fasting glucose between 100-125 mg/dL
• Willingness to comply with the demands of the experimental protocol
• Sedentary lifestyle

Exclusion Criteria

• Major medical condition
• Smokers
• Unable to perform moderate exercise
• Use of medications that alter glucose or lipid metabolism
• Pregnant or lactating

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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107 participants in 3 patient groups, including a placebo group

High Resistant Starch Potatoes

Experimental group

Description:

Subjects will receive 1 serving daily for 8 weeks during the weight loss group sessions.

Treatment:

Other: potatoes

Low Resistant Starch Potatoes

Experimental group

Description:

Subjects will receive 1 serving daily for 8 weeks during the weight loss group sessions.

Treatment:

Other: potatoes

Other Carbohydrate Source

Placebo Comparator group

Description:

Subjects will receive 1 serving daily for 8 weeks during the weight loss group sessions.

Treatment:

Other: other carbohydrate