Light and Sleep Fragmentation

Stanford University

Status and phase: Begins enrollment in 3 months; Phase 4

Conditions: Mild Cognitive Impairment; Mood Disorders; Sleep

Treatments: Behavioral: Light therapy

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT06009289

IRB-71788

Details and patient eligibility

About

This trial will examine scheduled exposure to bright light in the morning and afternoon as a countermeasure to sleep fragmentation in older individuals with mild cognitive impairment.

Enrollment: 120 estimated patients

Sex: All

Ages: 65 to 99 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Mild Cognitive Impairment
• Age >65

Exclusion criteria

• Severe depression
• Unstable psychiatric or medical disease
• Acute infection

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Sequential Assignment

Masking: Double Blind

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120 participants in 2 patient groups

Standard of care

Active Comparator group

Description:

One hour of daily bright light exposure beginning one hour after wake time.

Treatment:

Behavioral: Light therapy

Stepped care

Experimental group

Description:

One hour of daily bright light exposure in the afternoon

Treatment:

Behavioral: Light therapy