Light Emitting Diode (LED) for the Treatment of Wrinkles

RoseLab Skin Optics Laboratory

Status and phase: Completed; Phase 3; Phase 2

Conditions: Photoaging of Skin; Skin Aging

Treatments: Device: Sham light; Device: LumiPhase-R™, OPUSMED Inc. Montreal, Canada

Study type: Interventional

Funder types: Other

Identifiers

NCT00818246

LEDP-1

Details and patient eligibility

About

The purpose of this study was to determine whether light emitting diode (LED) therapy can improve skin appearance of human subjects with aged/photoaged skin. A reduction in rhytid depth as well as in skin surface roughness and in the degree of elastosis after LED treatments was expected.

Enrollment: 40 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• subjects with aged/photodamaged skin

Exclusion criteria

• Subjects were not allowed to participate in this study if they were taking cortisone (Prednisone), anticoagulant therapy, or any drug known to increase photosensitivity. In addition, during the 12 months preceding the study, subjects were required not to have used isotretinoin (Accutane), or applied topical steroids to the site to be treated. Moreover, previous laser or topical medication at the to-be-treated site was not permitted.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Sham light

Sham Comparator group

Description:

one side of the face was treated three times weekly for four consecutive weeks (12 treatments) with a Sham light on the experimental periorbital area

Treatment:

Device: Sham light

LED-treated

Experimental group

Description:

one side of the face was treated three times weekly for four consecutive weeks (12 treatments) with 660 nm Light emitting diode (LED) on the experimental periorbital area

Treatment:

Device: LumiPhase-R™, OPUSMED Inc. Montreal, Canada