Limb Remote Ischemic Preconditioning for Heart and Intestinal Protection During Laparoscopic Colorectal Surgery

Fei Li

Status: Unknown

Conditions: Laparoscopic Colorectal Surgery

Treatments: Procedure: Limb remote ischemic preconditioning (LRIP)

Study type: Interventional

Funder types: Other

Identifiers

NCT01832337

伦研批第E201215号

Details and patient eligibility

About

Remote ischaemic preconditioning may confer the cytoprotection in critical organs. The investigators hypothesized that limb remote ischemic preconditioning (RIPC) would reduce heart and gastrointestinal function injury in middle-aged and elderly patients undergoing elective laparoscopic colorectal surgery.

Enrollment: 120 estimated patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age >40 years old
• ASA I-II
• receive elective laparoscopic colorectal surgery
• written informed consent can be obtained

Exclusion criteria

• coagulation disorders
• patients with cardiac pacemaker
• patients with severe cardiac,or pulmonary,hepatic,renal disease ,or can not tolerate laparoscopic surgery
• patients with peripheral vascular disease affecting the upper limbs
• patients with mental,or hearing, vision disorder, who is not able to communicate with physicians
• difficult airways that can not receive rapid induction

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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120 participants in 1 patient group

precondition

Experimental group

Treatment:

Procedure: Limb remote ischemic preconditioning (LRIP)