LiPO Teen (the Lifestyle in Pregnancy and Offspring Teenagers

Odense University Hospital

Status: Enrolling

Conditions: Life Style, Healthy; Follow-up; Obesity; Gestational Weight Gain; Body Weight

Treatments: Behavioral: Lifestyle intervention Dietary advise and/or advise on physical activity

Study type: Interventional

Funder types: Other

Identifiers

NCT05774652

LiPO-Teen

Details and patient eligibility

About

The study is a follow-up of a Randomized Controlled Trial (RCT) performed in 2007-10 - the "Lifestyle in Pregnancy" LiP study.

The LiP study included 360 pregnant women with BMI ≥30 kg/m2 from Odense University Hospital and Aarhus University Hospital. The women were randomized to intervention with low-calorie diet and physical activity from gestational age 10-14 in pregnancy and until delivery - or to a standard care control group. The objective of the LiPO-Teen project is to perform a clinical follow-up study of the eligible 301 mothers who completed the trial until delivery with a liveborn child, and their 14 year-old offspring. The overall ambition is to understand whether lifestyle intervention in pregnancy prevents obesity and its complications across generations, with a specific focus on modifiable factors.

Full description

LiPO Teen (the Lifestyle in Pregnancy and Offspring Teenagers): Identification of modifiable risk factors for childhood obesity - a follow-up of a randomized controlled trial.

The objective of the LiPO-Teen project is to perform a clinical follow-up study of the eligible 301 mothers who completed the trial until delivery with a liveborn child, and their 14 year-old offspring.

In the original trial women were randomized 1:1 to intervention or control. The participants (both mother and child in pair) who completed the initial LiP study will be invited to a 2-hour examination now 14 years after the intervention during pregnancy to evaluate the effect of the intervention on both mother and child long term.

Enrollment: 301 estimated patients

Sex: All

Ages: 13 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Mothers in the initial LiP study selected at the baseline study in 2007-2010
• Teenagers of mothers in the initial LiP study

Exclusion criteria

• None

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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301 participants in 2 patient groups

Diet + physical activity

Experimental group

Description:

Diet + physical activity Dietary advise and advise on physical activity

Treatment:

Behavioral: Lifestyle intervention Dietary advise and/or advise on physical activity

Control group

No Intervention group

Description:

No intervention