Liposomal Lidocaine Gel for Oral Topical Anesthesia

University of Campinas, Brazil

Status and phase: Completed; Phase 1

Conditions: Anesthesia

Treatments: Drug: Lidocaine

Study type: Interventional

Funder types: Other

Identifiers

NCT01425840

112/2007

Details and patient eligibility

About

This blinded cross-over study aimed to evaluate the efficacy of topical liposome-encapsulated lidocaine on oral mucosa.

Full description

This blinded cross-over study aimed to evaluate the efficacy of topical liposome-encapsulated 2,5 and 5% lidocaine gel formulations on the palatal mucosa.

Enrollment: 40 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy

Exclusion criteria

• Volunteers were free from cardiac, hepatic, renal, pulmonary, neurological, gastrointestinal and haematological diseases, psychiatric disorders and allergy to local anesthetics

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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40 participants in 1 patient group

Liposomal lidocaine, topical anesthesia

Experimental group

Description:

Efficacy of Liposomal lidocaine in topical anesthesia.

Treatment:

Drug: Lidocaine