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This clinical trial will assess the performance of a liquid biopsy assay to identify cancer in indeterminant pulmonary nodules identified by CT screening of high-risk individuals and evaluate the capability of the liquid biopsy assay to monitor response to surgical resection.
Full description
This clinical study examines the feasibility of a liquid biopsy methylation assay to detect non-small lung cancer. First, the investigators will apply their liquid biopsy assay to screen for lung cancer in indeterminate pulmonary nodules suspicious for cancer. Second, the investigators will assess the utility of liquid biopsy to assess tumor dynamics after surgical resection with curative intent. Third, the investigators will assess the presence or absence of this methylation assay in healthy normal persons without a history of lung cancer.
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Inclusion and exclusion criteria
Indeterminate pulmonary nodule study cohort
Known lung cancer for surgical resection study cohort
Healthy volunteer cohort
Benign lung disease cohort
171 participants in 4 patient groups
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Central trial contact
Linda Garland, MD
Data sourced from clinicaltrials.gov
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